This means that people who microdose feel NO psychoactive effects- there’s no need to worry about “tripping out” and seeing floating rainbow clouds while you’re at work.
1. Improved mood and focus: A 2019 study of 278 microdosers (who used either mushrooms or LSD) found that 26.6% of participants experienced an improved mood and 14.8% reported increased focus. However, it's unclear from the study whether these effects were from LSD or psilocybin.
2. Increased creativity: Another 2019 study found that people who microdose LSD or psilocybin experienced increased creativity and open-mindedness. This may have to do with the fact that psilocybin allows different parts of the brain to communicate in new and different ways.
3. Improved mental health: A 2019 study found that some microdosers of LSD or psilocybin experienced decreased levels of depression and stress over a six week period. This may be due to the positive effect that the drugs may have on serotonin — a neurotransmitter that is partially responsible for mood. Psilocybin is a serotonin receptor antagonist, meaning it can help improve the bioavailability of neurotransmitter like serotonin.
Additionally, a 2019 study found that people who microdosed psychedelics along with receiving psychological support during and after their experience saw improvements in their PTSD, anxiety, and depression.